T cells are essential in the immune response against tumor cells, in addition, immunotherapies such as immune checkpoint blockade, adoptive T cell therapy, and CAR-T cells rely on these cells to trigger the elimination of tumor cells.
Epidermal Growth Factor (EGF) is a low molecular mass protein produced in a variety of tissues and cells. In tissue culture, EGF reduces or eliminates the need for serum and can be used in combination with other media additives and hormones. EGF has a variety of biological activities, including induction of cell proliferation, differentiation, migration, and morphological determination, and has important physiological and pathological roles.
Fibroblast Growth Factor (FGF) is a class of cell growth factors. 23 members of the FGF family have a wide range of mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. Aberrant activation of the signaling pathway is associated with the onset and progression of many diseases, including cancer, diabetes, and cardiovascular disease. Therefore, FGF and its receptors may become new targets for the treatment of these diseases.
Hematopoietic cytokines are a class of protein molecules that are produced in the body and regulate the hematopoietic process. Hematopoietic cytokines are used in biology primarily to promote or improve hematopoiesis and are commonly used to treat anemia, reduce chemotherapy-induced hematocrit, and aid in hematopoietic stem cell transplantation.